The role of Demodex folliculorum in pathogenesis of rosacea

Introduction and objective: Rosacea is a common chronic inflammatory disease that affects approximately 10% of the population globally. The exact pathogenesis rosacea remains unknown. However, there are considered several factors such as genetic predisposition, environmental impact, immune dysregulation, well presence microorganisms. aim study to review recent knowledge about relationship between Demodex folliculorum. information used in presented analysis was obtained by searching academic research databases: Google Scholar PubMed.
 An abbreviated description state knowledge: folliculorum microscopic mite resides hair follicles sebaceous glands skin. Current studies show plays an important role rosacea. That related with induction excessive pro-inflammatory skin response combined increase inflammation mediators. Moreover patients observed nearly 6-fold density comparison general population. Increased number mites associated local immunosuppression may predispose development not only acute course prolonged duration disease, but also higher probability recurrence.
 Summary: involved Moreover, parasite, it significantly decreases quality patient’s life. Therefore, severe should be examined for mites. In case detection, regardless its quantitative load, antiparasitic drug recommended.